It looks as if an angry giant stomped through overnight, crushing homes and twisting trees, after a​ tornado touched down in Bollinger County, Missouri.

At least five people were killed in the community of Glenallen and an unknown number of people were killed.

Houses have been shoved off their foundations or smashed into pieces. Strips of tin roofing were wrapped around the branches of trees that remained standing. Many other big trees were shredded into kindling or pulled out of the ground by their roots.

The tornado, which struck between 3:30 and 4 a.m. CDT Wednesday, damaged homes and blocked roads in the Glenallen, Marble Hill and Grassy areas south of St. Louis, Bollinger County Sheriff Casey Graham told KFVS.

(​FORECAST: Severe Weather Threat Pushes Toward The East)

"We can confirm there are multiple injuries and multiple fatalities associated with this storm," Missouri State Highway Patrol Sgt. Clark Parrott told The Weather Channel Wednesday morning, before the number of deaths was announced.

Parrot said he could barely comprehend the damage he was seeing as he drove in Wednesday morning.

B​ecause people could still be trapped in their homes, first responders were still in a search and rescue mode, he said.

P​arrot told Fox 2 he had seen widespread damage including semitractor-trailers blown over and homes and churches missing roofs.

"​This was a big one, I think," he said.

Missouri's Gov. Mike Parson said in a Facebook post, "Overnight, parts of Missouri experienced damaging severe storms, and we’ve received reports of a tornado in Bollinger County. At this time, fatalities have been confirmed and others have been injured.

"We appreciate the work of our first responders and the many neighbors who reached out to help their neighbors, and our prayers are with the loved ones of those who were killed during the storms."

The deaths in Bollinger County mean this is the 13th deadly tornado in the U.S. since the March 24 outbreak, according to weather.com senior meteorologist Jonathan Erdman.

An outbreak of tornadoes this past weekend reached from the South and the Midwest into the Northeast. Tornadoes, confirmed or suspected in 11 states, killed at least 33 people.

V​ideo from the scene Wednesday morning in Missouri showed a wall ripped off one side of a two-story home, with a large tree uprooted beside it. The roof was torn from another house.

T​he Missouri tornado was one of several reported overnight after severe weather fired up again on Tuesday.

“It was horrible,” homeowner Walt Humburg said. “It was one when it popped, and everything started going haywire, that’s when it got scary.”

M​ultiple Injuries in Illinois

A​ tornado caused damage in Lewistown, Illinois, about 36 miles southwest of Peoria. Multiple injuries were reported in Lewistown, according to a Facebook post from the Fulton County Emergency Services and Disaster Agency.

Damage was seen in Lewistown, Table Grove and Bryant, the agency said.

Donald J. Brown heard the twister heading for Bryant.

"It was just bawlin' and squallin'" Brown told WBBM. "And after it hit, stuff was flying around my kitchen. My windows were knocked out."

The storm knocked a tree limb and siding into his house.

"This is the worst we've seen it," he said. "Lucky the whole house is still standing."

“It was just horrifying,” Monica Kline, who lives in Bryant, told WMBD. “It’s not something anybody wants to experience.”

Kline said her family lost four vehicles, a camper, buildings, sheds and a carport.

“The garage is complete. We have a three-car garage over there, it’s completely gone,” she said.

A​ tornado also touched down in Lacona, Iowa, but there were no reports of damage. Lacona is about 25 miles south of the Des Moines metro area.

E​arlier Tuesday, thunderstorms caused a ground stop at Chicago O'Hare International Airport and high winds and hail caused damage in the Quad Cities area, including the town of Colona, Illinois.

Walls and roofs were blown off some buildings, and t​he National Weather Service determined the damage was caused by an EF2 tornado.

T​he roof was blown off a gas station/restaurant building and it landed on a neighboring building, according to the Quad City Times. Nine people were in the building, but no one was hurt. An employee in the gas station had minor injuries.

A wind gust of about 90 mph was reported in nearby Moline, Illinois.

The Quad Cities region sits on the Mississippi River and also includes the Rock Island, Illinois, and Davenport and Bettendorf in Iowa.

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